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Updated: Jul 17, 2026

Stable and Efficient Genetic Modification of Cells in the Adult Mouse V-SVZ for the Analysis of Neural Stem Cell Autonomous and Non-autonomous Effects
08:48

Stable and Efficient Genetic Modification of Cells in the Adult Mouse V-SVZ for the Analysis of Neural Stem Cell Autonomous and Non-autonomous Effects

Published on: February 17, 2016

通过β-分泌酶BACE1控制周围神经髓化

Michael Willem1, Alistair N Garratt, Bozidar Novak

  • 1Adolf Butenandt-Institute, Department of Biochemistry, Laboratory for Alzheimer's and Parkinson's Disease Research, Schillerstrasse 44, Ludwig-Maximilians-University, 80336 Munich, Germany.

Science (New York, N.Y.)
|September 23, 2006
PubMed
概括

贝塔位粉样蛋白前体蛋白分裂酶1 (BACE1) 对外围神经髓化至关重要. 由于影响神经素1的处理,BACE1缺乏会导致低髓化和轴突缺陷.

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