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Updated: May 1, 2026

Deficient Pms2, ERCC1, Ku86, CcOI in Field Defects During Progression to Colon Cancer
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在林奇综合征中预测MLH1和MSH2突变

Judith Balmaña1, David H Stockwell, Ewout W Steyerberg

  • 1Population Sciences Division, Dana-Farber Cancer Institute, and Division of Gastroenterology, Boston, Mass 02115, USA.

JAMA
|September 28, 2006
PubMed
概括

在风险患者中,MLH1/MSH2基因的林奇综合征突变很常见. 该PREMM(1,2) 模型使用个人和家庭癌症史准确预测突变概率,帮助基因测试策略.

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