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在林奇综合征中预测生殖基因突变和癌症风险

Sining Chen1, Wenyi Wang, Shing Lee

  • 1Department of Environmental Health Sciences, Johns Hopkins Bloomberg School of Public Health, Baltimore, Md 21205, USA. sichen@jhsph.edu

JAMA
|September 28, 2006
PubMed
概括

一个新的工具,MMRpro,准确预测林奇综合征 (遗传性非多重性结直肠癌) 的风险. 它通过识别可能从不匹配修复基因测试中受益的个人来改善高风险家庭的遗传咨询和癌症预防.

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