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Updated: Jul 8, 2026

In Situ Detection of Autoreactive CD4 T Cells in Brain and Heart Using Major Histocompatibility Complex Class II Dextramers
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Published on: August 1, 2014

与多发性硬化症相关的常见MHC单元型的功能性表观

Jon W Gregersen1, Kamil R Kranc, Xiayi Ke

  • 1Department of Clinical Immunology, Aarhus University Hospital, Skejby Sygehus, 8200 N, Aarhus, Denmark.

Nature
|September 29, 2006
PubMed
概括

与多发性硬化症相关的人类MHC HLA-DR2单元型表现出强烈的链接不平衡,可能通过积极选择维持. 其等位基因之间的功能相互作用可能解释了这一点,为免疫反应调节提供了洞察力.

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