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Updated: Jul 19, 2026

Identification of Cyclin-dependent Kinase 1 Specific Phosphorylation Sites by an In Vitro Kinase Assay
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Published on: May 3, 2018

对FOXO1的CDK2依赖酸化作为对DNA损伤的亡反应

Haojie Huang1, Kevin M Regan, Zhenkun Lou

  • 1Department of Biochemistry and Molecular Biology, Mayo Clinic College of Medicine, Rochester, MN 55905, USA.

Science (New York, N.Y.)
|October 14, 2006
PubMed
概括

循环素依赖激酶2 (CDK2) 通过控制FOXO1转录因子活性来调节DNA损伤后的细胞存活率. DNA损伤抑制CDK2,防止FOXO1酸化,促进细胞死亡.

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