简单的合成单体甲酸的简单合成
Weiping Su1, Youngjo Kim, Arkady Ellern
1Department of Chemistry, Iowa State University, Ames, Iowa 50011, USA.
Journal of the American Chemical Society
|October 19, 2006
概括
甲酸,新型的易斯酸,通过其中心激活基质. 一个二度性酸有效地催化反应,在有机合成和材料科学中展示了潜力.
科学领域:
- 有机金属化学 有机金属化学
- 超分子化学 超分子化学
- 易斯酸催化剂的使用
背景情况:
- 甲酸是三环分子,具有跨环形N --> Al键.
- 它们作为易斯酸起作用,在轴协调部位激活基质.
研究的目的:
- 为了合成和表征新型二维.
- 为了研究它们与各种基质的反应性.
- 探索它们在有机反应中的催化潜力.
主要方法:
- 用AlMe(3) 处理三-2-基-3,5-二甲基) 胺,以形成二度 (AlL) (2).
- 为了结构阐明,进行X射线衍射分析.
- 与氧气和的捐赠者发生反应,包括水和甲.
- 在甲和三甲基化反应中的催化试验.
主要成果:
- 二次性阿卢马特兰 (AlL) 的合成及其表征.
- 在与不同基质反应时形成各种 (2-6).
- 观察结构变化和变化的跨环环键距离.
- 甲6的水解形成一个复杂的框架7,存在于多态形式 (7a, 7b).
- 狄米尔甲酸1催化了2 - 三甲基氧烯酸甲二的合成,产量为95%.
结论:
- 立体甲酸是多用途的易斯酸,能够激活基质.
- 顶端连接体的协调影响了中心的电子特性.
- 藻可以在水解时形成复杂的超分子框架.
- 在有机转化过程中,Dimeric Alumatrane 1 具有显著的催化活性.
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