基酸酶H子单元是一种酸受体
Yuan-Yue Shen1, Xiao-Fang Wang, Fu-Qing Wu
1China State Key Laboratory of Plant Physiology and Biochemistry, China Agricultural University, 100094 Beijing, China.
Nature
|October 20, 2006
概括
在植物中发现的酸受体 (ABAR/CHLH) 特别结合ABA. 这种蛋白质调节了关键的植物生长和发育过程,包括口腔运动和种子发芽.
科学领域:
- 植物生物学 植物生物学
- 分子生物学分子生物学
- 生物化学 生物化学
背景情况:
- 酸 (ABA) 是一种关键的植物激素,调节着口腔孔径和种子发育.
- 调解这些重要生理过程的特定ABA受体仍然在很大程度上未被确定.
研究的目的:
- 为了识别和描述负责调解植物ABA信号的ABA受体.
- 阐明由CHLH编码的ABA结合蛋白 (ABAR) 在植物发育和ABA感知中的作用.
主要方法:
- 用ABA结合测定来确认Arabidopsis ABAR/CHLH对ABA的特定结合.
- 分析ABAR/CHLH在植物生理过程中的功能,如种子发芽,发芽后生长和口腔运动.
- 在各种植物组织中分析ABAR/CHLH的表达.
主要成果:
- 证实了阿拉比多普西斯ABAR/CHLH能够特别结合酸.
- ABAR/CHLH作为种子发芽,发芽后生长和口腔运动的积极调节者,证实其作为ABA受体的作用.
- 在绿色和非绿色组织中,ABAR/CHLH表现出无处不在的表达,这表明整个植物的ABA信号感知.
结论:
- 结合ABA的蛋白质ABAR/CHLH可以作为Arabidopsis中的真实的ABA受体.
- 在各种植物发育阶段和组织中,ABAR/CHLH在调解ABA反应方面发挥着重要作用.
- ABAR/CHLH的无处不在表达突出了其在全植物ABA信号感知和整合方面的潜力.
相关概念视频
Ligand-gated Ion Channels
11.4K
Ligand-gated ion channels are transmembrane proteins with a channel for ions to pass through and a binding site for a ligand. The channel opens only when a ligand attaches to the binding site.
Three Subfamilies of Ligand-gated Ion Channels
Ligand-gated ion channels fall into three subfamilies. The 'Cys-loop' includes the nicotinic acetylcholine receptors, γ-aminobutyric acid (GABA), glycine, and 5-hydroxytryptamine receptors. The second one is the 'Pore-loop' channels that...
Three Subfamilies of Ligand-gated Ion Channels
Ligand-gated ion channels fall into three subfamilies. The 'Cys-loop' includes the nicotinic acetylcholine receptors, γ-aminobutyric acid (GABA), glycine, and 5-hydroxytryptamine receptors. The second one is the 'Pore-loop' channels that...
11.4K
Cell Signaling in Plants
4.6K
Plant cells communicate to coordinate their cycle of growth, flowering and fruiting, and activities in roots, shoots, and leaves in response to the changing environmental conditions. Plant signaling is distinct from animal signaling. Plants primarily utilize enzyme-linked receptors, whereas the largest class of cell-surface receptors in animals are G-protein coupled receptors (GPCRs). Unlike animals, receptor tyrosine kinases are rare in plants. Instead, plants have a diverse class of...
4.6K
Ligand-Gated Ion Channel Receptor: Gating Mechanism
4.6K
Ligand-gated ion channels are transmembrane proteins that play a vital role in intercellular communication and functions of the nervous system. They allow the influx of ions across the membrane once the neurotransmitter binds, allowing the subsequent transmission of electrical excitation across the neurons. Other ligand-gated ion channels, like the γ-aminobutyric acid (GABA) receptor, permit anions like chloride into the cells on the binding of the GABA molecule. Their entry into the cell...
4.6K
Cholinergic Receptors: Muscarinic
4.9K
The pharmacological actions of acetylcholine are elicited via its binding to two families of cholinergic receptors or cholinoceptors, namely, muscarinic and nicotinic receptors. Muscarinic receptors are G protein-coupled receptors and have five subtypes, M1–M5. All mAChR subtypes are activated by acetylcholine and blocked by the antagonist, atropine.
The subtypes M1, M3, and M5 couple with the Gq subunit and activate the phospholipase C (PLC) activity, mobilizing intracellular Ca2+....
The subtypes M1, M3, and M5 couple with the Gq subunit and activate the phospholipase C (PLC) activity, mobilizing intracellular Ca2+....
4.9K
Cholinergic Receptors: Nicotinic
5.4K
Nicotinic receptors are ligand-gated ion channels that are activated by acetylcholine and nicotine. Upon activation, they cause a rapid increase in the permeability of cells to K+, Na+, and Ca2+, followed by depolarization and excitation. They are in the autonomic ganglia, skeletal neuromuscular junction, CNS, and adrenal medulla.
There are two types of nicotinic receptors: neuromuscular (NM/NM/N1) and neuronal (NN/NN/N2). The two families differ based on their location and selectivity to...
There are two types of nicotinic receptors: neuromuscular (NM/NM/N1) and neuronal (NN/NN/N2). The two families differ based on their location and selectivity to...
5.4K
Chemotaxis in E. coli
1.4K
Chemotaxis in Escherichia coli is a sensory-driven motility mechanism that enables bacteria to navigate chemical gradients, moving toward beneficial environments while avoiding harmful conditions. This process relies on a signal transduction system integrating external chemical cues with flagellar motor control.Chemoreceptors and Signal DetectionE. coli detects chemical gradients through methyl-accepting chemotaxis proteins (MCPs), which are membrane-bound chemoreceptors that sense attractants...
1.4K


