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人类胰岛素降解酶的结构揭示了一种新的基质识别机制

Yuequan Shen1, Andrzej Joachimiak, Marsha Rich Rosner

  • 1Ben-May Institute for Cancer Research, The University of Chicago, 929 East 57th Street, Chicago, Illinois 60637, USA.

Nature
|October 20, 2006
PubMed
概括

胰岛素降解酶 (IDE) 的结构揭示了它如何降解胰岛素和β-粉样蛋白. 调节IDE活性可以治疗糖尿病和阿尔茨海默病.

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