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一个PARACESTMRI对比剂来检测酶活性

Byunghee Yoo1, Marty D Pagel

  • 1Department of Biomedical Engineering, Case Western Reserve University, 10900 Euclid Avenue, Cleveland, OH 44106-7207, USA.

Journal of the American Chemical Society
|October 26, 2006
PubMed
概括

研究人员开发了一种智能对比剂,用于MRI检测caspase-3,这是一个关键的亡生物标志物. 这种药物在 caspase-3 活动时改变其磁共振信号,从而能够灵敏地检测被编程细胞死亡.

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