Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Characteristics and Functions of Blood01:26

Characteristics and Functions of Blood

Blood is specialized connective tissue comprising about 8% of the body mass. It has a thick, liquid extracellular matrix that contains cells, dissolved proteins, and electrolytes, making it five times more viscous than water. Blood is warm, around 38°C, and has an alkaline pH ranging from 7.35 to 7.45.
The primary function of blood is to transport oxygen and carbon dioxide between tissues and the lungs. Oxygenated blood is bright red, while oxygen-depleted blood is darker. It also carries...
Liver Physiology01:30

Liver Physiology

The liver, an essential organ in the human body, performs over 200 vital functions that can be broadly categorized into metabolic, hematological, endocrine regulation, and bile production.
Metabolic Regulation:
The liver is the central organ involved in regulating blood composition. It stabilizes blood glucose levels, maintaining them within the range of  70–110 mg/dL. When these levels drop, the liver breaks down glycogen reserves and releases glucose into the bloodstream. It can also...
Lipids: Dietary Sources and Requirements01:18

Lipids: Dietary Sources and Requirements

Lipids are an essential component of a balanced human diet. Triglycerides, which make up the majority of dietary lipids, are found in both saturated fats—commonly present in meat, dairy products, and certain tropical plants like coconut, and hydrogenated oils such as margarine and baking shortenings (trans fats)—and unsaturated fats, which are abundant in seeds, nuts, olive oil, and most vegetable oils. The main sources of cholesterol include egg yolks, various meats and organ meats, shellfish,...
Cholesterol: Significance and Regulation01:29

Cholesterol: Significance and Regulation

Although not a source of energy, cholesterol plays a significant role as a foundational structure for bile salts, steroid hormones, and vitamin D, as well as being a crucial component of plasma membranes. Approximately 15% of blood cholesterol is derived from our diet, with the remainder synthesized from acetyl CoA by the liver and intestines. Cholesterol is eliminated from the body through its conversion into bile salts, which are eventually discarded in the feces.
Considering cholesterol and...
Blood Studies for Cardiovascular System III: Serum Lipid Profile01:25

Blood Studies for Cardiovascular System III: Serum Lipid Profile

Understanding serum lipids is crucial for maintaining cardiovascular health and preventing heart disease and stroke.
Serum lipids are fats and fatty substances in the blood and are crucial for various bodily functions, including energy storage, cellular structure, and hormone production. Serum lipids consist of cholesterol, triglycerides, and phospholipids.
Cholesterol is a soft, fat-like substance found in all body cells. It is crucial for producing hormones, vitamin D, and substances that aid...
Hepatitis01:25

Hepatitis

Hepatitis is an inflammatory condition of the liver most commonly caused by hepatotropic viruses (A–E), though non-infectious causes such as alcohol and drugs also exist.Hepatitis AHepatitis A virus (HAV) is a non-enveloped RNA virus of the Picornaviridae family. It is primarily transmitted via the fecal-oral route, typically through ingestion of contaminated food or water. After ingestion, HAV enters the bloodstream through the oropharynx or intestinal epithelium and reaches the liver. The...

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

The global extent of the grassland biome and implications for the terrestrial carbon sink.

Nature ecology & evolution·2026
Same author

Functional Outcome and Complications in Management of Proximal Humerus Fractures Operated with Proximal Humerus Locking Plate.

Malaysian orthopaedic journal·2021
Same author

The Preparation of Manure with Night-Soil and Street Rubbish.

The Indian medical gazette·2017
Same author

Effects of Hofmeister salt series on gluten network formation: Part I. Cation series.

Food chemistry·2016
Same author

Effects of Hofmeister salt series on gluten network formation: Part II. Anion series.

Food chemistry·2016
Same author

A secretory leukocyte protease inhibitor variant with improved activity against lung infection.

Mucosal immunology·2015

相关实验视频

Updated: Jul 12, 2026

Isolation of Lipoprotein Particles from Chicken Egg Yolk for the Study of Bacterial Pathogen Fatty Acid Incorporation into Membrane Phospholipids
11:59

Isolation of Lipoprotein Particles from Chicken Egg Yolk for the Study of Bacterial Pathogen Fatty Acid Incorporation into Membrane Phospholipids

Published on: May 15, 2019

人体血中热过渡低密度脂蛋白

R J Deckelbaum, G G Shipley, D M Small

    Science (New York, N.Y.)
    |October 24, 1975
    PubMed
    概括

    人体血中低密度脂蛋白经历了可逆的液晶到液相变化,涉及胆固醇在体温周围的胆固醇. 这种过渡需要在脂蛋白结构内有一个富含胆固醇的区域.

    科学领域:

    • 生物物理学的生物物理.
    • 脂质代谢 脂质代谢是什么
    • 结构生物学 结构生物学

    背景情况:

    • 低密度脂蛋白 (LDL) 对于人体血中的胆固醇运输至关重要.
    • 了解LDLs的结构动态对于理解脂质代谢和心血管健康至关重要.
    • 以前的研究表明,LDLs具有复杂的结构性质,但相位过渡在很大程度上仍未被探索.

    研究的目的:

    • 为了研究人体血低密度脂蛋白的热行为.
    • 阐明在生理温度下LDL结构转变背后的分子机制.
    • 确定胆固醇在LDL结构动态中的作用.

    主要方法:

    • 不同扫描热量计 (DSC) 检测热过渡.
    • 用X射线散射技术分析结构变化.
    • 分析纯化的人类血LDLs.

    主要成果:

    • 在LDL中观察到广泛的可逆热过渡,发生在人体体温附近.
    • 热度测量和X射线数据确定了这种过渡是液晶到液态相变的变化.
    • 阶段过渡与LDL中的胆固醇成分直接相关,需要一个富含胆固醇的域.

    更多相关视频

    Assessing Insulin Clearance in Mice via In Situ Liver Perfusion
    07:30

    Assessing Insulin Clearance in Mice via In Situ Liver Perfusion

    Published on: December 13, 2024

    High-Density Lipoprotein-Specific Phospholipid Efflux Assay
    07:08

    High-Density Lipoprotein-Specific Phospholipid Efflux Assay

    Published on: September 30, 2025

    相关实验视频

    Last Updated: Jul 12, 2026

    Isolation of Lipoprotein Particles from Chicken Egg Yolk for the Study of Bacterial Pathogen Fatty Acid Incorporation into Membrane Phospholipids
    11:59

    Isolation of Lipoprotein Particles from Chicken Egg Yolk for the Study of Bacterial Pathogen Fatty Acid Incorporation into Membrane Phospholipids

    Published on: May 15, 2019

    Assessing Insulin Clearance in Mice via In Situ Liver Perfusion
    07:30

    Assessing Insulin Clearance in Mice via In Situ Liver Perfusion

    Published on: December 13, 2024

    High-Density Lipoprotein-Specific Phospholipid Efflux Assay
    07:08

    High-Density Lipoprotein-Specific Phospholipid Efflux Assay

    Published on: September 30, 2025

    结论:

    • 人类的LDLs表现出一种温度依赖的相位过渡,涉及胆固醇.
    • 这种从液晶状态到液态状态的过渡是一种合作过程.
    • 胆固醇丰富区域的存在对于LDL中观察到的这种热行为至关重要.