在长期旅行者中预防疟疾
Lin H Chen1, Mary E Wilson, Patricia Schlagenhauf
1Travel Medicine Center, Division of Infectious Diseases, Mount Auburn Hospital, Cambridge, Mass 02238, USA. lchen@hms.harvard.edu
JAMA
|November 9, 2006
概括
长期旅行者面临更高的疟疾风险,并且经常不充分利用保护措施. 个人预防策略,包括化学预防和个人保护,对于长期预防疟疾至关重要.
科学领域:
- 旅行 医学 旅行 医学
- 传染性疾病 传染性疾病
- 热带医学 热带医学
背景情况:
- 长期旅行 (≥6个月) 遇到独特的疟疾预防挑战.
- 现有的指导方针主要关注短期旅行者和Plasmodium falciparum.
- 长途旅行的疟疾预防需要专门考虑.
研究的目的:
- 为了评估长期旅行者的疟疾风险.
- 审查个人防护措施的进展.
- 评估长期疟疾化学预防的安全性和有效性,并探索预防策略,包括P. vivax复发预防.
主要方法:
- 在科学出版物 (MEDLINE,PubMed) 中进行了全面的文献搜索,截至2006年7月.
- 包括关于长期旅行,预防疟疾,化学预防和驱虫剂的研究.
- 额外的数据来源于文献,论文和会议记录,没有语言限制.
主要成果:
- 与短期旅行者相比,长期旅行者具有更高的疟疾风险.
- 个人防护措施的不足使用和化学预防的不良遵守被注意到.
- 存在各种策略,每个策略都有好处和坏处;假冒药物是一个重大问题,目前的第一线治疗方案无法防止P. vivax复发.
结论:
- 长期旅行者预防疟疾是复杂的,需要专家的旅行医学咨询.
- 在这种人口群体中,为有效预防疟疾提供个性化建议至关重要.
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