泰拉马斯对前额叶皮层空间视觉处理的影响
Marc A Sommer1, Robert H Wurtz
1Department of Neuroscience, the Center for the Neural Basis of Cognition, and the Center for Neuroscience at the University of Pittsburgh, University of Pittsburgh, Pittsburgh, Pennsylvania 15260, USA. sommer@bns.pitt.edu
大脑使用尾随性放电,是运动指令的内部副本,在眼睛运动时保持视觉稳定. 这项研究揭示了一条与前额皮层视觉处理相关的冠状动脉排放的thalamocortical通路.
科学领域:
- 神经科学是一个神经科学.
- 感官处理 感官处理
- 发动机控制器 发动机控制器
背景情况:
- 大脑必须区分自我生成的感官输入与外部刺激.
- 假设随机放电 (机动指令的内部副本) 有助于处理自我运动.
- 这种机制可以解释视觉稳定性,尽管眼睛的动.
研究的目的:
- 建立 corolar 放电和视觉处理之间的联系.
- 为了确定神经回路中介视觉稳定在saccades期间.
- 为了研究体冠状管排泄在前皮层视觉处理中的作用.
主要方法:
- 在皮层的正面眼球领域的电生理学记录.
- 来自泰拉马斯的冠状排泄通道的扰乱.
- 分析神经元受体场移动之前的眼球运动.
主要成果:
- 确定了一条从 thalamus (中背核) 到正面眼球领域的尾随性放电通路.
- thalamic冠状管排放被证明是驱动前额叶皮质神经元在saccades之前的视觉受体场的空间转移.
- 这条通路的中断损害了神经元视觉处理,证明了功能依赖.
结论:
- 结论:结论性放电与视觉处理之间建立了第一个直接联系.
- 一个神经电路涉及thalamocortical投影用于视觉稳定性在saccades被划定.
- 这为了解其他感官系统的相继性放电提供了一个框架.
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