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对N1999A2的酶选择性合成

Nan Ji1, Hardwin O'Dowd, Brad M Rosen

  • 1Department of Chemistry and Chemical Biology, Harvard University, Cambridge, MA 02138, USA.

Journal of the American Chemical Society
|November 16, 2006
PubMed
概括

研究人员开发了一种21个步骤的选择性合成,用于enediyne抗生素N1999A2,首次实现了固体形式. 这一突破使得对这种复杂分子的进一步研究成为可能.

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