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图布利辛D的总合成量

Hillary M Peltier1, Jeffrey P McMahon, Andrew W Patterson

  • 1Department of Chemistry, University of California, Berkeley, California 94720, USA.

Journal of the American Chemical Society
|December 15, 2006
PubMed
概括

通过使用新的 tert-butanesulfinamide 方法,首次实现了 tubulysin D 的总合成. 这种高效的途径可以快速进行模拟合成,用于研究管素的生物活性.

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