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X-Ray Crystallography to Study the Oligomeric State Transition of the Thermotoga maritima M42 Aminopeptidase TmPep1050
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在Abeta10-35单体中形成Asp23-Lys28盐桥的动力学

Bogdan Tarus1, John E Straub, D Thirumalai

  • 1Department of Chemistry, Boston University, Boston, Massachusetts 02215, USA.

Journal of the American Chemical Society
|December 15, 2006
PubMed
概括

研究了粉样β蛋白 (Abeta蛋白) D23-K28盐桥形成. 分子动力学模拟表明,水排放有助于阿贝塔的寡合化和稳定结构.

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