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Updated: Jul 10, 2026

A High-throughput-compatible FRET-based Platform for Identification and Characterization of Botulinum Neurotoxin Light Chain Modulators
10:30

A High-throughput-compatible FRET-based Platform for Identification and Characterization of Botulinum Neurotoxin Light Chain Modulators

Published on: December 27, 2013

肉毒神经毒素B识别其蛋白质受体具有高亲和力和特异性

Rongsheng Jin1, Andreas Rummel, Thomas Binz

  • 1Howard Hughes Medical Institute, Stanford University, Stanford, California 94305, USA.

Nature
|December 15, 2006
PubMed
概括

肉毒神经毒素 (BoNTs) 通过synaptotagmin II和化物结合细胞. 对BoNT/B结合的这种结构性洞察力推动了针对这种神经毒素的疫苗和抑制剂的开发.

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