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Updated: Jul 18, 2026

Sequence-specific and Selective Recognition of Double-stranded RNAs over Single-stranded RNAs by Chemically Modified Peptide Nucleic Acids
09:04

Sequence-specific and Selective Recognition of Double-stranded RNAs over Single-stranded RNAs by Chemically Modified Peptide Nucleic Acids

Published on: September 21, 2017

PNA-DNA双重体,三重体和四重体与跨cyclopentane单位稳定

Ethan A Englund1, Qun Xu, Mark A Witschi

  • 1Laboratory of Bioorganic Chemistry, Department of Health and Human Services, National Institute of Diabetes, Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD 20892, USA.

Journal of the American Chemical Society
|December 21, 2006
PubMed
概括

使用 (S,S) - 跨cyclopentane 胺单元的酸核酸 (PNA) 骨干修饰增强了稳定性. 这种tcyp结合改善了用于生物医学应用的PNA-DNA双重,三重和四重结构.

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