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毛 ribozyme 中 G8 的活性位点标记:对结构和机制的影响

Jason M Thomas1, David M Perrin

  • 1Department of Chemistry, University of British Columbia, 2036 Main Mall, Vancouver, BC, Canada V6T 1Z1.

Journal of the American Chemical Society
|December 21, 2006
PubMed
概括

研究人员在毛针 ribozyme 中确定了 guanosine 8 (G8) 作为催化过程中的关键成分. 这一发现,使用亲和度标签,表明G8可能充当一般基,类似于RNase A.

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