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Updated: Jul 18, 2026

Efficient Isolation Protocol for B and T Lymphocytes from Human Palatine Tonsils
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Published on: November 16, 2015

通过B淋巴细胞的可溶补体受体抑制免疫反应

T Hebell1, J M Ahearn, D T Fearon

  • 1Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21205.

Science (New York, N.Y.)
|October 4, 1991
PubMed
概括

研究人员开发出一种可溶性CR2 (CD21) 融合蛋白,可以抑制B细胞激活. 这一发现为免疫系统研究中的幽默性免疫抑制提供了潜在的新策略.

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Overview
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B Cell Activation and Differentiation

The adaptive immune response, a sophisticated defense mechanism, relies on the activation and differentiation of B lymphocytes, or B cells. These processes enable our bodies to mount a tailored response against specific pathogens such as bacteria, free virus particles, toxins, and parasites.
When naive B cells encounter a specific antigen that can bind to the B cell receptor (BCR) on their surface, they undergo sensitization to respond to the antigen's presence. Sensitization begins with...