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Updated: May 12, 2026

Purification of the Cystic Fibrosis Transmembrane Conductance Regulator Protein Expressed in Saccharomyces cerevisiae
15:12

Purification of the Cystic Fibrosis Transmembrane Conductance Regulator Protein Expressed in Saccharomyces cerevisiae

Published on: May 10, 2014

核三酸盐是开启CFTR化通道所需的

M P Anderson1, H A Berger, D P Rich

  • 1Howard Hughes Medical Institute, Department of Internal Medicine, University of Iowa College of Medicine, Iowa City 52242.

Cell
|November 15, 1991
PubMed
概括

细胞质ATP对于开放化CFTR通道至关重要,核酸结合域1 (NBD1) 的水解可能足以激活. 这解释了CFTR突变如何破坏化通道功能.

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