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Updated: May 10, 2026

Chromatin Immunoprecipitation from Human Embryonic Stem Cells
10:36

Chromatin Immunoprecipitation from Human Embryonic Stem Cells

Published on: July 22, 2008

希斯 arginine甲基化调节了早期小鼠胚胎中的多能性

Maria-Elena Torres-Padilla1, David-Emlyn Parfitt, Tony Kouzarides

  • 1The Wellcome Trust/Cancer Research UK Gurdon Institute, University of Cambridge, Tennis Court Road, Cambridge CB2 1QN, UK.

Nature
|January 12, 2007
PubMed
概括

早期的小鼠胚胎细胞显示出基于基质子修饰的独特的发育潜力. 基因组H3氨酸甲基化标记了用于内部细胞质的细胞,影响了早期胚胎发育和细胞命运的决定.

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Generation of Human Primordial Germ Cell-like Cells at the Surface of Embryoid Bodies from Primed-pluripotency Induced Pluripotent Stem Cells12:06

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Published on: January 11, 2019

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The histone proteins have a flexible N-terminal tail extending out from the nucleosome. These histone tails are often subjected to post-translational modifications such as acetylation, methylation, phosphorylation, and ubiquitination. Particular combinations of these modifications form “histone codes” that influence the chromatin folding and tissue-specific gene expression.
Acetylation
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