运动测试开始时心率增加的预后值
Nicholas J Leeper1, Frederick E Dewey, Euan A Ashley
1Stanford University Medical Center, Stanford University Medical School, Calif, USA. nleeper@cvmed.stanford.edu
Circulation
|January 24, 2007
概括
运动期间心率快速上升预示着更好的生存率. 然而,运动心率峰值和杜克跑步机得分是进行跑步机测试的患者心血管预后的更强有力的预测因素.
科学领域:
- 心脏病学 心脏病学
- 运动生理学 运动生理学
- 预测生物标志物 预测生物标志物
背景情况:
- 动态运动对初始心率反应的预后价值正在调查中.
- 之前的研究使用了跑步机测试以外的炼模式.
研究的目的:
- 在临床跑步机测试期间评估早期心率参数的预后意义.
- 为了确定初始心率变化是否预测死亡风险.
主要方法:
- 分析了接受临床跑步机测试的1959名患者.
- 用多变量Cox生存分析来评估结果.
- 随访时间平均为5.4年,有197人死于各种原因,74人死于心血管疾病.
主要成果:
- 在初始工作负载下心率上升的降低与全因死亡率的增加相关.
- 心率在运动能力的三分之一上升预测了所有原因和心血管风险.
- 峰值运动心率增加是心血管预后最强的心率预测因素.
结论:
- 快速的初始心率上升与改善的生存率有关.
- 与早期心率参数相比,高峰运动心率和杜克跑步机得分是心血管预后的优越预测指标.
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