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核受体Nur77由6-mercaptopurine的激活可以防止Neointima的形成

Nuno M M Pires1, Thijs W H Pols, Margreet R de Vries

  • 1Gaubius Laboratory, TNO-Quality of Life, Leiden, The Netherlands.

Circulation
|January 24, 2007
PubMed
概括

6 - 默卡普图 (6-MP) 通过激活核受体Nur77.7来抑制血管光滑肌肉细胞的增殖和复原. 这种激活减少了DNA合成和neointima形成,提供了潜在的治疗本体静止.

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