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福克斯O是血统受限的冗余瘤抑制剂,并调节内皮细胞平衡

Ji-Hye Paik1, Ramya Kollipara, Gerald Chu

  • 1Department of Medical Oncology, Dana-Farber Cancer Institute, Brigham and Women's Hospital, and Harvard Medical School, Boston, MA 02115, USA.

Cell
|January 27, 2007
PubMed
概括

哺乳动物叉头盒O (FoxO) 转录因子是关键的瘤抑制剂. 删除所有FoxOs会促进癌症,强调它们在预防瘤疾病和维持血管平衡中的作用.

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