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Updated: Jan 10, 2026
01:24
Nephrotic Syndrome I : Introduction
Published on: June 19, 2025
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通过多普勒超声波检测冠状动脉微栓塞在患有稳定胸痛的患者中,这些患者正在接受选择性穿皮冠状动脉干预
Philipp Bahrmann1, Gerald S Werner, Gerd Heusch
1Clinic of Internal Medicine I, Friedrich Schiller University, Erlanger Allee 101, 07740 Jena, Germany. philipp.bahrmann@med.uni-jena.de
Circulation
|January 31, 2007
概括
穿皮冠状动脉干预 (PCI) 期间的微栓塞与肌结有关. 冠状动脉内多普勒超声波显示,周围手术性心肌梗塞患者中微栓塞的频率较高,证实了微栓塞是原因.
科学领域:
- 心血管医学 心血管医学
- 干预心脏病学 干预心脏病学
- 诊断性的超声波检查
背景情况:
- 冠状动脉内多普勒导线可以在皮肤冠状动脉干预 (PCI) 期间实时检测微栓塞.
- 研究了多普勒检测微栓塞频率和选择性PCI期间肌病发病率之间的关系.
研究的目的:
- 确定PCI期间通过冠状动脉多普勒检测到的微栓塞的频率与周围手术性心肌梗塞 (pMI) 的发生是否相关.
- 评估微栓塞对PCI后系统性炎症和微血管功能的影响.
主要方法:
- 使用冠状动脉多普勒超声波对象的微栓塞频率的比较,对象是接受选择性PCI的pMI和没有pMI的患者.
- 分析了临床,程序特征,高灵敏度C-反应蛋白水平和心脏托罗邦素I升高.
主要成果:
- 与没有pMI的患者相比,pMI患者在PCI后的冠状动脉微栓塞总数显著增加 (27±10对16±8,P<0.001).
- 在PCI后的高灵敏性C反应蛋白水平在pMI组中升高 (12.6±10.4对比6.1±5.1 mg/L,P<0.05).
- 微血栓计数与I型托波宁升高,冠状动脉流速储量和基线平均峰值速度相关.
结论:
- 在PCI期间冠状动脉微栓塞的更高频率与pMI显著相关.
- 微栓塞有助于PCI后观察到的全身炎症反应和微血管损伤.
- 冠内多普勒超声波证实微栓塞是选择性PCI患者的pMI的原因.
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