没有明显的心脏病的突然心律失常死亡.
H J Wellens1, R Lemery, J L Smeets
1Department of Cardiology, Academic Hospital Maastricht, University of Limburg, Maastricht, The Netherlands.
Circulation
|January 1, 1992
概括
突然心律不整的死亡可以发生在未知心脏病的情况下. 常见的对药物不反应的心室心律失常症表明预后不佳,这表明需要建立一个全球患者登记册.
科学领域:
- 心脏病学 心脏病学
- 电力生理学 电力生理学
- 突然的心脏病死亡.
背景情况:
- 在没有明显的心脏病的个体中,循环崩和突发心律失常死亡可能发生.
- 这些事件的潜在机制和最佳管理策略仍然不清楚.
研究的目的:
- 报告一系列经历循环崩和/或突然心律失常死亡的患者.
- 调查该患者队列中的临床特征,心律失常和结果.
- 探索特定电生理学发现的预后意义和抗心律失常疗法的作用.
主要方法:
- 一系列病例报告了9名患有循环系统崩的患者.
- 在复苏期间记录心律不整,包括心室动和心室动.
- 评估频繁的早期心室早跳和不持续的多态心室低心率.
- 评估药物治疗反应和长期随访.
主要成果:
- 在9名患者中,有7名患者经历了记录的心室动;其中一人有心室飞.
- 四名患者有频繁的早期心室过早跳动,经常有不持续的多态心室动脉慢心.
- 药物治疗未能抑制子宫外活动与不良结果有关,包括突然死亡和复发性心律失常.
- 一名患者在21个月后突然死亡;另外两名患者有复发性症状发作.
结论:
- 在没有明显的心脏病的情况下,突然心律失常死亡也可能发生,心室心律失常是关键特征.
- 持续频繁的心室外皮,特别是当对抗节律失常药物无反应时,具有显著的不良预后影响.
- 鉴于这些病例的罕见性和不确定性,建议建立一个全球注册表,以更好地了解和管理这些病例.
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