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Updated: Jul 17, 2026

Semi-quantitative Detection of RNA-dependent RNA Polymerase Activity of Human Telomerase Reverse Transcriptase Protein
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通过转录RNA聚合酶II进行CPD损伤识别

Florian Brueckner1, Ulrich Hennecke, Thomas Carell

  • 1Munich Center for Integrated Protein Science CiPS, Ludwig-Maximilians-Universität München, Feodor-Lynen-Strasse 25, 81377 Munich, Germany.

Science (New York, N.Y.)
|February 10, 2007
PubMed
概括

细胞在转录合修复 (TCR) 过程中阻断RNA聚合酶II (Pol II) 通过错误地将尿素纳入相反的DNA损伤. 这种停滞对于DNA修复至关重要,防止聚合酶的进展,直到病变被移除.

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