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Synthesis of Wavelength-shifting DNA Hybridization Probes by Using Photostable Cyanine Dyes
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用蓝色发光量子点和染料标记的单链DNA进行DNA杂交检测

Hui Peng1, Lijuan Zhang, Tanja H M Kjällman

  • 1Polymer Electronic Research Centre, The University of Auckland, Private Bag 92019, Auckland, New Zealand.

Journal of the American Chemical Society
|February 24, 2007
PubMed
概括

No abstract available in PubMed .

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Labeling DNA Probes03:31

Labeling DNA Probes

DNA probes are fragments of DNA labeled with a reporter tag to enable their detection or purification. The resulting labeled DNA probes can then hybridize to target nucleic acid sequences through complementary base-pairing, and may be used to recover or identify these regions.
Radioisotopes, fluorophores, or small molecule binding partners like biotin or digoxigenin, are the most widely used reporter tags for labeling DNA probes. These labels can be attached to the probe DNA molecule via...
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