氧化与五坐标Fe ((III) ((Porphyrin) 酸盐中间体Fe ((Por) ((ONO) 在升华固体中的反应
Tigran S Kurtikyan1, Astghik A Hovhannisyan, Manya E Hakobyan
1Molecule Structure Research Centre (MSRC) NAS, 375014 Yerevan, Armenia. kurto@netsys.am
Journal of the American Chemical Society
|March 7, 2007
概括
铁烯模型与氧化反应,形成和复合物. 这些复合物经历异构和分解,揭示了对/氧化相互作用的洞察力.
科学领域:
- 生物有机化学 生物有机化学
- 协调化学 协调化学
- 频谱学是一种光谱学.
背景情况:
- 血红蛋白在生物系统中起着至关重要的作用,通常与氧化 (NOx) 相互作用.
- 了解铁氨酸复合物与NOx的反应性对于模拟这些生物过程至关重要.
- 氧化对环境具有重要意义,并参与各种化学转化.
研究的目的:
- 研究铁甲模型与氧化 (NO2和NO) 之间的详细反应机制.
- 使用光谱方法来表征由此产生的铁化,铁酸盐和铁酸盐复合物.
- 阐明这些中间复合物的异构化路径和稳定性.
主要方法:
- 里埃变换红外光谱法 (FTIR) 光谱法
- 光学光谱学是指光学光谱学.
- 同位素标记实验 同位素标记实验
- 密度函数理论 (DFT) 的计算.
主要成果:
- 从NO2添加到Fe (II) 酸盐中形成5坐标酸盐复合物[Fe(Por) ((η1-ONO) ].
- 进一步的反应产生一个6坐标酸盐复合物[Fe(Por) ((η2-O2NO) ].
- 与NO的相互作用会导致酸盐-酸盐复合物,这些复合物以酸盐-酸盐复合物[Fe () () (η1-NO2) (NO) ]进行异构.
- 同位素标记支持分子内同位素化机制.
- 在6坐标复合体中观察到Fe(III) 中心的旋转状态变化.
结论:
- 铁氨酸与NO2和NO发生复杂的反应,形成各种与结合的物种.
- 分子内异构化是-基复合物的转化中的关键途径.
- 这些复合物的稳定性和反应性为血-NOx相互作用提供了模型.
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