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Updated: Jul 10, 2026

Phosphopeptide Analysis of Rodent Epididymal Spermatozoa
09:30

Phosphopeptide Analysis of Rodent Epididymal Spermatozoa

Published on: December 30, 2014

分泌途径的分子剖析

J E Rothman1, L Orci

  • 1Program of Cellular Biochemistry and Biophysics, Rockefeller Research Laboratory, Sloan-Kettering Institute, New York, New York 10021.

Nature
|January 30, 1992
PubMed
概括

研究人员结合了无动物细胞生物化学和酵母遗传学,揭示了真核细胞分泌途径. 这项研究揭示了囊泡运输和融合的保存机制和简单的外层结构.

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Overview of Secretory Vesicles01:33

Overview of Secretory Vesicles

Secretory vesicles, also known as dense core vesicles (DCVs), are membrane-bound vesicles that transport secretory proteins, such as hormones or neurotransmitters. Regulated secretory vesicles transport proteins from the trans-Golgi network to the exterior of the cell. Proteins present in regulated secretory vesicles are required to be rapidly exocytosed in large amounts upon a specific stimulus.
Various proteins regulate the aggregation of molecules inside the secretory vesicles. Chromogranins...