相关实验视频

Updated: Jul 16, 2026

Combined DNA-RNA Fluorescent In situ Hybridization (FISH) to Study X Chromosome Inactivation in Differentiated Female Mouse Embryonic Stem Cells
15:54

Combined DNA-RNA Fluorescent In situ Hybridization (FISH) to Study X Chromosome Inactivation in Differentiated Female Mouse Embryonic Stem Cells

Published on: June 14, 2014

在X不激活过程中,XIST非编码RNA的功能与BRCA1独立

Cuiying Xiao1, Judith A Sharp, Misako Kawahara

  • 1Genetics of Development and Disease Branch, National Institute of Diabetes and Digestive and Kidney Diseases, 10/9N105, National Institutes of Health, Bethesda, MD 20892, USA.

Cell
|March 14, 2007
PubMed
概括

BRCA1突变增加了癌症的风险. 然而,这项研究发现BRCA1不能调节XISTRNA定位或基因表达在不活跃的X染色体上,这挑战了以前的模型.

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Quick Fluorescent In Situ Hybridization Protocol for Xist RNA Combined with Immunofluorescence of Histone Modification in X-chromosome Inactivation12:42

Quick Fluorescent In Situ Hybridization Protocol for Xist RNA Combined with Immunofluorescence of Histone Modification in X-chromosome Inactivation

Published on: November 26, 2014

A Non-random Mouse Model for Pharmacological Reactivation of Mecp2 on the Inactive X Chromosome08:27

A Non-random Mouse Model for Pharmacological Reactivation of Mecp2 on the Inactive X Chromosome

Published on: May 22, 2019

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