门诊患者患有动脉血症的一年心血管事件率
Ph Gabriel Steg1, Deepak L Bhatt, Peter W F Wilson
1Département de Cardiologie, Hôpital Bichat-Claude Bernard, Paris, France. gabriel.steg@bch.aphp.fr
JAMA
|March 22, 2007
概括
患有已确定的动脉血栓症的患者每年面临高的心血管事件率. 具有多个动脉疾病位置显著增加心血管事件的风险在一年内.
科学领域:
- 心血管医学 心血管医学
- 流行病学 流行病学
- 公共卫生 公共卫生
背景情况:
- 有限的数据存在于当前的心血管 (CV) 事件率在社区环境中稳定的动脉血症患者.
- 在单个国际队列中,冠状动脉疾病 (CAD),脑血管疾病 (CVD) 和外周动脉疾病 (PAD) 的不同事件率仍未评估.
研究的目的:
- 为了确定门诊患者当代,国际,一年CV事件率.
- 评估已确定的动脉疾病患者的事件率与具有多重动脉瘤风险因素的患者的事件率.
主要方法:
- 为了持续健康而减少动脉血症 (REACH) 登记册在2003年至2004年期间在国际上注册了68,236名患者.
- 该队列包括已确诊的动脉样硬化性动脉疾病 (CAD,PAD,CVD) 或至少三个危险因素的患者.
- 分析了一年内心血管死亡率,心肌梗塞 (MI) 和中风.
主要成果:
- 一年内心血管死亡,心脏病发作或中风的总比率为4.24%,既定疾病患者为4.69%,高风险患者为2.15%.
- 对于已确定的疾病,发病率为4.52% (CAD),6.47% (CVD) 和5.35% (PAD).
- 随着症状性动脉疾病部位的数量增加,事件发生率从5.31% (仅风险因素) 增加到26.27% (三个部位).
结论:
- 已确诊的动脉样硬化性动脉疾病或有风险的门诊患者每年 CV 事件发生率高.
- 多个动脉疾病部位的存在显著提高了心血管事件的1年风险.
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