基质竞争是Wee1无活化的超敏感性来源

Sun Young Kim1, James E Ferrell

  • 1Department of Chemical and Systems Biology, Stanford University School of Medicine, Center for Clinical Sciences Research, Stanford, CA 94305-5174, USA.

Cell
|March 27, 2007
PubMed
概括

线粒调节器Wee1和Cdk1形成一个双负反循环. 竞争机制驱动了Wee1对Cdk1的超敏感反应,确保了突然的细胞周期过渡.