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Lysobactin 的总合成

Aikomari Guzman-Martinez1, Ryan Lamer, Michael S VanNieuwenhze

  • 1Department of Chemistry and Biochemistry, University of California at San Diego, La Jolla, California 92093, USA.

Journal of the American Chemical Society
|April 17, 2007
PubMed
概括

新型抗生素lysobactin对MRSA和VRE等耐药细菌表现出强烈的活性. 它独特的抑制酸甘形成的机制为具有挑战性的感染提供了有前途的新治疗策略.

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