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哺乳动物生殖细胞中的表观遗传决定

Christopher B Schaefer1, Steen K T Ooi, Timothy H Bestor

  • 1Department of Genetics and Development, College of Physicians and Surgeons of Columbia University, New York, NY 10032, USA.

Science (New York, N.Y.)
|April 21, 2007
PubMed
概括

哺乳动物的生殖细胞在特定序列上建立DNA甲基化模式,沉默反转移子和印记基因. 这一过程显示出显著的性二态,是遗传基因表达控制的关键.

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