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Updated: May 1, 2026

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在核细胞质蛋白上O结合β-N-乙糖胺循环的循环

Gerald W Hart1, Michael P Housley, Chad Slawson

  • 1Department of Biological Chemistry, Johns Hopkins University, School of Medicine, 725 North Wolfe Street, Baltimore, Maryland 21205-2185, USA. gwhart@jhmi.edu

Nature
|April 27, 2007
PubMed
概括

在所有生物体中,O-链的β-N-乙糖胺 (O-GlcNAc) 动态添加和去除,作为营养传感器. 这一过程影响蛋白质信号传递,并与糖尿病和神经退行等疾病有关.

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