相关实验视频

维生素和衰老:NAD+合成的途径

John M Denu1

  • 1Department of Biomolecular Chemistry, School of Medicine and Public Health, University of Wisconsin, 1300 University Avenue, Madison, WI 53706, USA. jmdenu@wisc.edu <jmdenu@wisc.edu>

Cell
|May 8, 2007
PubMed
概括

尼古丁胺胺,一种新的NAD+前体,通过调节Sir2脱乙酶活性来延长酵母的寿命. 这种寿命延长效应独立于卡路里限制,为衰老研究提供了新的见解.

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