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Methods to Increase the Sensitivity of High Resolution Melting Single Nucleotide Polymorphism Genotyping in Malaria
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改善对抗疟疾药物耐药性的监测

Jean-Paul Chretien1, Mark Fukuda, Harald Noedl

  • 1US Department of Defense Global Emerging Infections Surveillance & Response System, Silver Spring, Md 20910, USA. jean-paul.chretien@na.amedd.army.mil

JAMA
|May 25, 2007
PubMed
概括

No abstract available in PubMed .

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Malaria01:29

Malaria

Malaria pathogenesis in humans reflects a delicate interplay between parasite biology and host response. Clinical illness reflects a host’s immune response to the parasite’s asexual replication cycle, which is often asymptomatic in individuals with partial immunity. From the parasite's perspective, transmission between mosquito and human with minimal host pathology is evolutionarily advantageous. Among the six Plasmodium species infecting humans, P. falciparum and P. vivax dominate in global...
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