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Author Spotlight: Enhancing Coronary Artery Revascularization
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在人类Ago2中,一个mRNA m7G帽结合式动机抑制了翻译

Marianthi Kiriakidou1, Grace S Tan, Styliani Lamprinaki

  • 1Department of Medicine, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA. kiriakim@uphs.upenn.edu

Cell
|May 26, 2007
PubMed
概括

人类阿尔戈纳特 (Ago) 蛋白与微RNA (miRNA) 结合,以调节基因表达. 研究人员在Ago蛋白中发现了一种模式,该蛋白结合m(7) G盖,通过阻止eIF4E招募来抑制翻译启动.

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