有氧间歇训练对心力衰竭患者中等持续训练的优越心血管效应:一项随机研究
Ulrik Wisløff1, Asbjørn Støylen, Jan P Loennechen
1Department of Circulation and Medical Imaging, Norwegian University of Science and Technology, Olav Kyrres gt. 9, 7489 Trondheim, Norway. ulrik.wisloff@ntnu.no
Circulation
|June 6, 2007
概括
高强度间歇训练显著改善了心血管功能,并在心力衰竭的老年患者中逆向左心室重塑. 中等强度的运动也提高了生活质量,但高强度的训练产生了更好的结果.
科学领域:
- 心脏病学 心脏病学
- 运动生理学 运动生理学
- 老年病的医生 老年病的医生
背景情况:
- 慢性心力衰竭 (CHF) 的症状通过运动训练而减少,但有益适应的最佳强度仍在争论中.
- 心血管疾病发病率随着年龄的增长而上升,但老年人 (>70岁) 往往被排除在研究之外.
- 这项研究研究了老年心脏病发作后CHF患者的中度和高强度运动.
研究的目的:
- 为了比较中等强度持续训练 (MICT) 与有氧间歇训练 (AIT) 对心血管功能和预后在患有心脏衰竭后的老年患者的影响.
- 评估运动强度对左心室 (LV) 重塑,有氧能力,内皮功能和生活质量的影响.
主要方法:
- 27名老年患者 (平均年龄75.5岁) 患有稳定的心脏衰竭被随机分为三组:MICT (70%心率峰值),AIT (95%心率峰值) 或对照组.
- 参与者接受了12周的培训 (每周3次),并接受了最佳的医疗治疗.
- 评估了心血管功能,LV重塑,内皮功能,线粒体功能和生活质量.
主要成果:
- 与MICT相比,AIT导致峰值氧气消耗 (VO2峰值) (46%对14%,P<0.001) 的改善显著增加.
- AIT引发了反向LV重塑,使LV的终端透缩和终端静缩体积分别降低了18%和25%,并使LV射出分数增加了35%.
- AIT显示内皮功能和线粒体功能得到了更大的改善;两组运动都改善了生活质量得分.
结论:
- 运动强度对于逆转LV重塑和增强心脏衰竭患者的有氧能力,内皮功能和生活质量至关重要.
- 在这个老年人群中,高强度间歇训练与中等强度训练相比,对心血管功能和重塑有更好的益处.
- 研究结果支持在心力衰竭的老年人心脏康复计划中量身定制的运动强度.
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