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Updated: Jun 20, 2026

Identifying DNA Mutations in Purified Hematopoietic Stem/Progenitor Cells
11:06

Identifying DNA Mutations in Purified Hematopoietic Stem/Progenitor Cells

Published on: February 24, 2014

在衰老过程中,DNA修复对血造干细胞具有限制性

Anastasia Nijnik1, Lisa Woodbine, Caterina Marchetti

  • 1Henry Wellcome Building for Molecular Physiology, Oxford University, Oxford OX3 9DU, UK.

Nature
|June 8, 2007
PubMed
概括

修复DNA损伤对于干细胞衰老至关重要. 在小鼠中,一种特定的DNA结合酶IV突变显示,受损的DNA双链断裂修复加速了干细胞的枯竭和衰老.

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