相关实验视频

Updated: Jul 8, 2026

Investigating the Function of Deep Cortical and Subcortical Structures Using Stereotactic Electroencephalography: Lessons from the Anterior Cingulate Cortex
09:00

Investigating the Function of Deep Cortical and Subcortical Structures Using Stereotactic Electroencephalography: Lessons from the Anterior Cingulate Cortex

Published on: April 15, 2015

HDAC6拯救神经退行并提供了自和UPS之间的重要联系

Udai Bhan Pandey1, Zhiping Nie, Yakup Batlevi

  • 1Department of Neurology, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104, USA.

Nature
|June 15, 2007
PubMed
概括

自补偿了神经退行症中受损的泛素-蛋白酶体系统 (UPS) 功能. 基因组脱乙酶6 (HDAC6) 是这种补偿机制的关键,为神经退行性疾病提供潜在的治疗点.

更多相关视频

Benefits of Cardiac Resynchronization Therapy in an Asynchronous Heart Failure Model Induced by Left Bundle Branch Ablation and Rapid Pacing12:45

Benefits of Cardiac Resynchronization Therapy in an Asynchronous Heart Failure Model Induced by Left Bundle Branch Ablation and Rapid Pacing

Published on: December 11, 2017

Regulating Schwann Cell Growth by Nanosecond Pulsed Electric Field for Peripheral Nerve Regeneration In Vitro09:24

Regulating Schwann Cell Growth by Nanosecond Pulsed Electric Field for Peripheral Nerve Regeneration In Vitro

Published on: May 3, 2024

相关概念视频

Conservation of AC Power01:15

Conservation of AC Power

The principle of power preservation is applicable to both ac and dc circuits. This principle, when applied to AC power, asserts that the complex, real, and reactive powers produced by the source are equal to the total complex, real, and reactive powers absorbed by the loads. When two load impedances are connected in parallel to an ac source V, the complex power provided by the source can be calculated using the relation
Power System Distribution01:25

Power System Distribution

Power system distribution involves delivering electrical energy from power plants to consumers through a network of transmission and distribution systems. The process begins at power plants, where energy from coal, gas, nuclear, water, and wind is converted into electrical energy. These plants use three-phase generators, typically rated between 50 to 1300 MVA, with terminal voltages ranging from a few kV to 20 kV, depending on the size and age of the units.
The transmission system is designed...
Distribution Reliability and Automation01:25

Distribution Reliability and Automation

Distribution reliability in electrical power systems is critical for ensuring an uninterrupted power supply to consumers at minimal cost. According to IEEE Standard Terms, reliability is the probability that a device will function without failure over a specified time period or amount of usage. For electric power distribution, this translates to maintaining continuous power supply and addressing customer concerns over power outages. Several indices, as defined by IEEE Standard 1366-2012, are...
Heart Failure VI: Adjunct Therapies01:22

Heart Failure VI: Adjunct Therapies

Additional therapies for treating patients with heart failure (HF) may include procedural interventions, supplemental oxygen, the management of sleep disorders, and nutritional therapy.Procedural InterventionsImplantable Cardioverter-Defibrillator: For patients at risk of life-threatening arrhythmias due to severe left ventricular dysfunction, an Implantable Cardioverter-Defibrillator (ICD) can detect and terminate these arrhythmias, preventing sudden cardiac death and improving survival rates.
Cardiomyopathy V: Interprofessional Care01:29

Cardiomyopathy V: Interprofessional Care

Managing cardiomyopathy involves addressing underlying or precipitating causes, treating heart failure with medications, and implementing dietary changes and a balanced exercise and rest regimen.Lifestyle ModificationsCardiomyopathy patients should adopt a low-sodium diet to reduce fluid retention and manage heart failure. A personalized exercise and rest plan helps maintain physical fitness without overstraining the heart. Avoiding alcohol and tobacco is essential to prevent further damage to...