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Updated: Feb 6, 2026

Author Spotlight: Unraveling the Impact of Mechanical Ventilation on Diaphragm Function and Patient Outcomes
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通过血管输送小干扰RNA到中枢神经系统

Priti Kumar1, Haoquan Wu, Jodi L McBride

  • 1The CBR Institute for Biomedical Research and Department of Pediatrics, Harvard Medical School, Boston, Massachusetts 02115, USA.

Nature
|June 19, 2007
PubMed
概括

一种新型的,RVG-9R,促进了小干扰RNA (siRNA) 穿过血脑屏障的传递,用于神经疾病治疗. 这种可以使脑细胞中的向基因沉默,提供一种安全的治疗方法.

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Measuring DNA Damage and Repair in Mouse Splenocytes After Chronic In Vivo Exposure to Very Low Doses of Beta- and Gamma-Radiation11:24

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A protocol to evaluate changes in DNA damage levels and DNA repair capacity that may be induced by chronic in vivo low dose irradiation in mouse spleen lymphocytes, by measuring phosphorylated histone H2AX, a marker of DNA double-strand breaks, using flow cytometry is presented.
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