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SRC-3协作激活器的功能寿命由酸依赖的无处不在的时钟调节

Ray-Chang Wu1, Qin Feng, David M Lonard

  • 1Department of Molecular and Cellular Biology, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, USA.

Cell
|June 19, 2007
PubMed
概括

调节的SRC-3 (类固醇受体辅激剂-3) 的无处不在控制其激活和降解. 这种依赖酸化的过程起到"转录时间钟"的作用,平衡协激活器功能并防止瘤发生.

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