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Updated: May 5, 2026

Static Adhesion Assay for the Study of Integrin Activation in T Lymphocytes
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Published on: June 13, 2014

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焦点粘附激酶自抑制的结构基础

Daniel Lietha1, Xinming Cai, Derek F J Ceccarelli

  • 1Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA 02115, USA.

Cell
|June 19, 2007
PubMed
概括

焦粘附激酶 (FAK) 是由其FERM域调节的,它抑制了激酶活性. 结构分析揭示了FAK激活如何涉及FERM移位和酸化,从而使细胞信号传递成为可能.

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Examining the Dynamics of Cellular Adhesion and Spreading of Epithelial Cells on Fibronectin During Oxidative Stress10:57

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