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Updated: Jul 14, 2026

Determining the Likelihood of Variant Pathogenicity Using Amino Acid-level Signal-to-Noise Analysis of Genetic Variation
07:15

Determining the Likelihood of Variant Pathogenicity Using Amino Acid-level Signal-to-Noise Analysis of Genetic Variation

Published on: January 16, 2019

在鹿特丹研究中,常见的NOS1AP变异与延长的QTc间隔有关

Albert-Jan L H J Aarnoudse1, Christopher Newton-Cheh, Paul I W de Bakker

  • 1Department of Epidemiology and Biostatistics, Erasmus Medical Center, PO Box 2040, 3000 CA, Rotterdam, The Netherlands.

Circulation
|June 20, 2007
PubMed
概括

在老年人中,NOS1AP基因的常见变异显著影响QT间隔的持续时间. 然而,这项研究发现,这些遗传变异与心脏突然死亡风险之间没有明确的联系.

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