将DNA复制限制在代谢周期的减少阶段,可以保护基因组完整性

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Updated: Jul 14, 2026

Inducing a Site Specific Replication Blockage in E. coli Using a Fluorescent Repressor Operator System
11:19

Inducing a Site Specific Replication Blockage in E. coli Using a Fluorescent Repressor Operator System

Published on: August 21, 2016

Zheng Chen1, Elizabeth A Odstrcil, Benjamin P Tu

  • 1Department of Biochemistry, University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX 75390, USA.

Science (New York, N.Y.)
|June 30, 2007
PubMed
概括

酵母细胞有一个周期性的代谢周期,在糖解和呼吸之间交替. 这个循环与细胞分裂和DNA复制协调,保持基因组完整性.

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Assessment of Global DNA Double-Strand End Resection using BrdU-DNA Labeling coupled with Cell Cycle Discrimination Imaging

Published on: April 28, 2021

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