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Updated: Jul 13, 2026

Stimulation of Cytoplasmic DNA Sensing Pathways In Vitro and In Vivo
11:44

Stimulation of Cytoplasmic DNA Sensing Pathways In Vitro and In Vivo

Published on: September 18, 2014

DAI (DLM-1/ZBP1) 是一个细胞质DNA传感器,也是先天免疫反应的激活剂

Akinori Takaoka1, Zhichao Wang, Myoung Kwon Choi

  • 1Department of Immunology, Graduate School of Medicine and Faculty of Medicine, University of Tokyo, Hongo 7-3-1, Bunkyo-ku, Tokyo 113-0033, Japan.

Nature
|July 10, 2007
PubMed
概括

研究人员确定DAI (IFN调节因子的DNA依赖激活剂) 是一个关键的细胞核DNA传感器. 这种蛋白质增强了I型干扰素的产生,这对于对病原体和自身免疫性疾病的天生的免疫力至关重要.

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