Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Phenotypic Profiling of Human Stem Cell-Derived Midbrain Dopaminergic Neurons09:21

Phenotypic Profiling of Human Stem Cell-Derived Midbrain Dopaminergic Neurons

2.0K
This protocol describes the cell culturing of human midbrain dopaminergic neurons, followed by immunological staining and the generation of neuronal phenotypic profiles from acquired microscopic high-content images allowing the identification of phenotypic variations due to genetic or chemical...
2.0K
Reliable Identification of Living Dopaminergic Neurons in Midbrain Cultures Using RNA Sequencing and TH-promoter-driven eGFP Expression10:54

Reliable Identification of Living Dopaminergic Neurons in Midbrain Cultures Using RNA Sequencing and TH-promoter-driven eGFP Expression

10.0K
In Parkinson's Disease (PD), Substantia Nigra (SNc) dopaminergic neurons degenerate, leading to motor dysfunction. Here we report a protocol for culturing ventral midbrain neurons from a mouse expressing eGFP driven by a Tyrosine Hydroxylase (TH) promoter sequence, harvesting individual fluorescent neurons from the cultures, and measuring their transcriptome using...
10.0K
Isolation, Culture and Long-Term Maintenance of Primary Mesencephalic Dopaminergic Neurons From Embryonic Rodent Brains08:45

Isolation, Culture and Long-Term Maintenance of Primary Mesencephalic Dopaminergic Neurons From Embryonic Rodent Brains

14.5K
The causes of degeneration of midbrain dopaminergic neurons during Parkinson’s disease are not fully understood. Cellular culture systems provide an essential tool for study of the neurophysiological properties of these neurons. Here we present an optimized protocol, which can be utilized for in vitro modeling of...
14.5K
Environmental Modulations of the Number of Midbrain Dopamine Neurons in Adult Mice09:35

Environmental Modulations of the Number of Midbrain Dopamine Neurons in Adult Mice

9.2K
This protocol describes two different environmental manipulations and a concurrent brain infusion protocol to study environmentally-induced brain changes underlying adaptive behavior and brain repair in adult...
9.2K
Primary Culture of Mouse Dopaminergic Neurons11:58

Primary Culture of Mouse Dopaminergic Neurons

39.1K
Dopaminergic neurons play a vital regulatory role in the brain. Their loss is associated with Parkinson's disease. In this video, we show how to generate primary cultures of central dopaminergic neurons from embryonic mouse mesencephalon. Such cultures are useful to study the extreme vulnerability of these neurons to various...
39.1K
Comprehensive Profiling of Dopamine Regulation in Substantia Nigra and Ventral Tegmental Area09:54

Comprehensive Profiling of Dopamine Regulation in Substantia Nigra and Ventral Tegmental Area

26.4K
Dopamine is distinctly regulated in the midbrain nuclei, which contain the cell bodies and dendrites of the dopamine neurons. Here we describe a dissection and sample-handling approach to maximize results, and thus conclusions and insights, on dopamine regulation in the midbrain nuclei of the substantia nigra (SN) and ventral tegmental area (VTA) in...
26.4K

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Large-scale analogue quantum simulation using atom dot arrays.

Nature·2026
Same author

Genomic-based animal management in the early- and late-finishing system of Hanwoo cattle.

Animal : an international journal of animal bioscience·2025
Same author

High-fidelity sub-microsecond single-shot electron spin readout above 3.5 K.

Nature communications·2025
Same author

Grover's algorithm in a four-qubit silicon processor above the fault-tolerant threshold.

Nature nanotechnology·2025
Same author

Evaluation of non-additive genetic effects on carcass and meat quality traits in Korean Hanwoo cattle using genomic models.

Animal : an international journal of animal bioscience·2024
Same author

High-fidelity initialization and control of electron and nuclear spins in a four-qubit register.

Nature nanotechnology·2024

相关实验视频

Updated: Jan 8, 2026

Environmental Modulations of the Number of Midbrain Dopamine Neurons in Adult Mice
09:35

Environmental Modulations of the Number of Midbrain Dopamine Neurons in Adult Mice

Published on: January 20, 2015

9.2K

来自独立来源的两个不可区分的电子之间的干扰.

I Neder1, N Ofek, Y Chung

  • 1Braun Center for Submicron Research, Department of Condensed Matter Physics, Weizmann Institute of Science, Rehovot 76100, Israel.

Nature
|July 20, 2007
PubMed
概括

量子交换统计允许两个独立电子之间的干扰. 研究人员在电子马赫-泽恩德干扰仪中观察到轨道纠,证明了交叉相关中的阿哈罗诺夫-博姆振荡.

科学领域:

  • 量子物理学的量子物理学
  • 凝聚物质物理学 凝聚物质物理学
  • 量子光学就是量子光学.

背景情况:

  • 量子干扰是基本的,通过交换统计数据观察到单粒子和双粒子系统.
  • 实验验证二粒子干扰,特别是电子干扰,由于源和同步问题而具有挑战性.
  • 之前的电子实验集中在自相对应 (射击噪声) 上,与观察光子聚合的光学实验不同.

研究的目的:

  • 通过实验证明两个独立电子束之间的量子干扰和轨道纠.
  • 使用马赫-泽恩德干扰仪实现汉伯里布朗和特维斯实验的电子模拟.
  • 调查阿哈罗诺夫-博姆流量对电子电流波动和交叉相关性的作用.

主要方法:

  • 在量子霍尔效应模式中利用边缘通道来创建电子马赫-泽恩德干扰仪.
  • 将两个独立的,相互不连贯的电子束分成四个轨迹,封闭一个阿哈罗诺夫-博姆流.
  • 测量了个体电流的自相关性和相反点上的电流波动之间的交叉相关性.

主要成果:

  • 单个电子电流及其射击噪声 (自相关) 显示不依赖于阿哈罗诺夫-博姆流量.
  • 当前波动之间的交叉相关性测量显示出明显的阿哈罗诺夫-博姆振荡.
  • 这些振荡提供了两个电子束之间的轨道纠的证据.

更多相关视频

Primary Culture of Mouse Dopaminergic Neurons
11:58

Primary Culture of Mouse Dopaminergic Neurons

Published on: September 8, 2014

39.1K
Comprehensive Profiling of Dopamine Regulation in Substantia Nigra and Ventral Tegmental Area
09:54

Comprehensive Profiling of Dopamine Regulation in Substantia Nigra and Ventral Tegmental Area

Published on: August 10, 2012

26.4K

相关实验视频

Last Updated: Jan 8, 2026

Environmental Modulations of the Number of Midbrain Dopamine Neurons in Adult Mice
09:35

Environmental Modulations of the Number of Midbrain Dopamine Neurons in Adult Mice

Published on: January 20, 2015

9.2K
Primary Culture of Mouse Dopaminergic Neurons
11:58

Primary Culture of Mouse Dopaminergic Neurons

Published on: September 8, 2014

39.1K
Comprehensive Profiling of Dopamine Regulation in Substantia Nigra and Ventral Tegmental Area
09:54

Comprehensive Profiling of Dopamine Regulation in Substantia Nigra and Ventral Tegmental Area

Published on: August 10, 2012

26.4K

结论:

  • 该实验成功地证明了独立电子束之间的量子干扰和轨道纠.
  • 交叉相关度测量是一种敏感的探测器,用于检测电子系统中的轨道纠.
  • 这些发现为使用电子纠的新量子信息处理方案铺平了道路.