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Updated: Jul 7, 2026

Quantification of Information Encoded by Gene Expression Levels During Lifespan Modulation Under Broad-range Dietary Restriction in C. elegans
09:23

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大脑的IRS2信号协调寿命和营养平衡

Akiko Taguchi1, Lynn M Wartschow, Morris F White

  • 1Howard Hughes Medical Institute, Division of Endocrinology, Children's Hospital Boston, Harvard Medical School, Boston, MA 02115, USA.

Science (New York, N.Y.)
|July 21, 2007
PubMed
概括

在小鼠中减少胰岛素受体基质-2 (Irs2) 信号传递,特别是在大脑中,延长了长达18%的寿命. 这种干预改善了老年小鼠的新陈代谢,并减少了氧化应激.

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